Evaluation of optical quality in pterygium patients with a new modified sutureless and glue-free method

BMC Ophthalmol. 2021 Nov 27;21(1):410. doi: 10.1186/s12886-021-02180-2.

Abstract

Background: Modified sutureless and glue-free method is an effective and novel surgical approach for pterygium. We aim to evaluate optical quality in pterygium treated with the new method and investigate the clinical application of the Optical Quality Analysis System (OQAS) and Anterior segment optical coherence tomography (AS-OCT) to evaluate the pterygium surgery.

Methods: A total of 52 eyes of 52 patients with pterygium were randomly divided into 2 groups. After surgical excision, the bare sclera was placed with a tight fit limbal conjunctival autograft fixed via the modified sutureless and glue-free method in group 1 (26 eyes) and conventional sutures in group 2 (26 eyes). Objective scattering index (OSI), modulation transfer function (MTF) and Strehl ratio (SR) were measured using OQAS in both groups during the perioperative period. Pterygium diameter was measured on AS-OCT. Ocular surface disease index (OSDI) questionnaire also was used.

Results: The group 1 had significantly lower mean OSI, higher mean MTF, and higher mean SR at 1 month and 3 months after surgery (p < 0.05). The group 1 had significantly lower mean OSDI at 1 month (p < 0.05), while was similar to group 2 at 3 months (p > 0.05). Pterygium diameter positively correlated with OSI (r = 0.528, p < 0.001), while it negatively correlated with MTF (r = - 0.501, p < 0.001) and SR (r = - 0.174, p = 0.217) before operation.

Conclusions: The modified sutureless and glue-free method might be more advantageous in improving the optical quality during early postoperative recovery times and pterygium diameter affected optical quality. OQAS can be reliably used to evaluate postoperative outcomes.

Keywords: Glue-free; Optical quality; Optical quality analysis system; Pterygium.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Conjunctiva / surgery
  • Fibrin Tissue Adhesive
  • Follow-Up Studies
  • Humans
  • Pterygium* / surgery
  • Suture Techniques
  • Sutures
  • Transplantation, Autologous

Substances

  • Fibrin Tissue Adhesive