CHIASM, the human brain albinism and achiasma MRI dataset

Robert J Puzniak; Brent McPherson; Khazar Ahmadi; Anne Herbik; Jörn Kaufmann; Thomas Liebe; Andre Gouws; Antony B Morland; Irene Gottlob; Michael B Hoffmann; Franco Pestilli

doi:10.1038/s41597-021-01080-w

CHIASM, the human brain albinism and achiasma MRI dataset

Sci Data. 2021 Nov 26;8(1):308. doi: 10.1038/s41597-021-01080-w.

Authors

Robert J Puzniak¹, Brent McPherson^#², Khazar Ahmadi^#¹, Anne Herbik¹, Jörn Kaufmann³, Thomas Liebe⁴, Andre Gouws⁵, Antony B Morland⁶, Irene Gottlob⁷, Michael B Hoffmann^{1

8}, Franco Pestilli⁹

Affiliations

¹ Visual Processing Lab, Department of Ophthalmology, Otto-von-Guericke-University, Leipziger-Str. 44 (H. 60B), 39120, Magdeburg, Germany.
² Pestilli Lab, Department of Psychological and Brain Sciences, Indiana University Bloomington, 1101 E 10th Street, Bloomington, Indiana, 47405, USA.
³ Department of Neurology, Otto-von-Guericke-Universität, Leipziger-Str. 44 (H. 60A/60B), 39120, Magdeburg, Germany.
⁴ Department of Psychiatry and Psychotherapy, Jena University Hospital, Philosophenweg 3, 07742, Jena, Germany.
⁵ York Neuroimaging Centre, Department of Psychology, University of York, York, YO10 5DD, United Kingdom.
⁶ Centre for Neuroscience, Hull-York Medical School, Heslington, York, YO10 5DD, United Kingdom.
⁷ Department of Neuroscience, Psychology & Behaviour, University of Leicester, University Road, Leicester, LE1 7RH, United Kingdom.
⁸ Center for Behavioral Brain Sciences, Otto-von-Guericke-Universität, Universitätsplatz 2 (G24-205), 39106, Magdeburg, Germany.
⁹ Department of Psychology, Center for Perceptual Systems, Center for Theoretical and Computational Neuroscience, Institute for Neuroscience, The University of Texas, 108 E Dean Keeton Street, Austin, Texas, 78712, United States. pestilli@utexas.edu.

^# Contributed equally.

Abstract

We describe a collection of T1-, diffusion- and functional T2*-weighted magnetic resonance imaging data from human individuals with albinism and achiasma. This repository can be used as a test-bed to develop and validate tractography methods like diffusion-signal modeling and fiber tracking as well as to investigate the properties of the human visual system in individuals with congenital abnormalities. The MRI data is provided together with tools and files allowing for its preprocessing and analysis, along with the data derivatives such as manually curated masks and regions of interest for performing tractography.

Publication types

Dataset
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Albinism / diagnostic imaging*
Brain / diagnostic imaging*
Congenital Abnormalities / diagnostic imaging
Diffusion Magnetic Resonance Imaging*
Humans
Optic Chiasm / abnormalities*
Optic Chiasm / diagnostic imaging

Abstract

Publication types

MeSH terms

Grants and funding