Biosynthesis of silver nanoparticles from Mukia maderaspatana (L) and their biological activities

Pak J Pharm Sci. 2021 Sep;34(5(Supplementary)):1837-1847.

Abstract

Nanotechnology is a field of science that consists of atoms, molecules and supramolecular molecules that create nanoparticles ranging in size from 1-100nm. Silver nanoparticles are widely used that are considered as effective antimicrobial agents. In this paper, the antioxidant activity of biosynthesized SNPs were analyzed by the DPPPH activity, hydrogen peroxide activity, hydroxyl RSA, TAC, TFC; their results confirmed that the phenolic compounds of this plant peels extracts enhanced the antioxidant and antiglycation activity with respect to silver nanoparticles. Biosynthesized nanoparticles of this plant extracts also showed strong zone of inhibition against the different Xanthomas, Pseudomonas and E. coli. This study concluded that biosynthesized nanoparticles of Mukia maderaspatna (M.M) plant peels extracts have the great biological activities i.e. antiglycation, antioxidant and antibacterial. More research is needed to know the exact dose rate and to compare the different dose combination of the plant with the strong antibiotic agents against these bacteria.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antioxidants / pharmacology
  • Bacteria / drug effects
  • Cucurbitaceae / chemistry*
  • Escherichia coli / drug effects
  • Fruit / chemistry
  • Green Chemistry Technology
  • Metal Nanoparticles / chemistry*
  • Microbial Sensitivity Tests
  • Pakistan
  • Particle Size
  • Plant Extracts / pharmacology
  • Pseudomonas / drug effects
  • Silver Compounds / chemistry*
  • Xanthomonas / drug effects

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Plant Extracts
  • Silver Compounds