Novel therapeutic options for treatment of recurrent implantation failure

Fertil Steril. 2021 Dec;116(6):1449-1454. doi: 10.1016/j.fertnstert.2021.10.025.

Abstract

Despite the challenges in studying recurrent implantation failure, progress is currently being made in therapeutic options to help those who suffer from recurrent implantation failure. Three of the most promising therapeutic options for recurrent implantation failure include immune therapies such as peripheral blood mononuclear cells, platelet rich plasma and subcutaneous granulocyte-colony stimulating factor.

Keywords: Recurrent implantation failure; granulocyte colony stimulating factor; peripheral blood mononuclear cells; platelet rich plasma.

Publication types

  • Review

MeSH terms

  • Embryo Implantation / physiology*
  • Embryo Transfer / methods*
  • Embryo Transfer / trends
  • Female
  • Fertilization in Vitro / methods
  • Fertilization in Vitro / trends
  • Granulocyte Colony-Stimulating Factor / administration & dosage*
  • Humans
  • Immunotherapy / methods*
  • Immunotherapy / trends
  • Leukocytes, Mononuclear / physiology
  • Leukocytes, Mononuclear / transplantation
  • Platelet-Rich Plasma / physiology*
  • Pregnancy
  • Recurrence
  • Treatment Failure*
  • Treatment Outcome

Substances

  • Granulocyte Colony-Stimulating Factor