Preconception diabetes remission, a viable approach to reduce pregnancy risks in women with recent diagnosis of Type 2 diabetes: Case report and clinical discussion

Clin Obes. 2022 Feb;12(1):e12495. doi: 10.1111/cob.12495. Epub 2021 Nov 25.

Abstract

The prevalence of women diagnosed with Type 2 diabetes (T2D) at fertile age has been increasing over the last few decades, and pregnancy with T2D is associated with increased maternal and foetal risks. In the last few years, studies have shown that focusing on aggressive weight loss in individuals recently diagnosed with T2D can lead to diabetes remission. Here, we present a case report of a woman who achieved diabetes remission after massive weight loss and had an uncomplicated pregnancy. Diabetes remission before pregnancy could be offered to motivated women with T2D as a safe way to reduce the risks of pregnancy. As a plausible hypothesis, dedicated studies are warranted to demonstrate if this approach can lead to reduced adverse maternal and foetal outcomes.

Keywords: Type 2 diabetes; diabetes in pregnancy; diabetes remission; pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Diabetes Mellitus, Type 2* / diagnosis
  • Female
  • Humans
  • Pregnancy
  • Prenatal Care
  • Weight Loss