[Oncogeriatric assessment: The first step in personalizing cancer treatment in the elderly]

Rev Med Interne. 2022 Mar;43(3):152-159. doi: 10.1016/j.revmed.2021.10.006. Epub 2021 Nov 23.
[Article in French]

Abstract

With aging worldwide population and the high incidence of cancer in the population of people over 75 years old, there is a need for oncologists and geriatricians to strengthen their collaboration to improve elderly patients care. Complexity of cancer and aging issues must be considered simultaneously to establish a personalized care plan. Thus, the G8 is a screening tool that allows to identify patients who should benefit from a geriatric assessment, which is a key step in the management process. This specific evaluation offers a multidisciplinary approach to functional, psychological, nutritional, cognitive and social status and has demonstrated its prognostic value in terms of choice of treatment but also in terms of patient survival. In nearly 20% of cases, the geriatric assessment leads to a change in the choice of treatment, and at one year the initial care plan is not carried out in a quarter of cases. The presence of malnutrition and functional impairment leading to dependence on basic activities of daily living had a significant impact on this change in therapeutic choice. Survival is not only impacted by malnutrition and functional impairment but also by the presence of severe comorbidities and thymic and neurocognitive impairment. The patient's choice must remain at the center of the elaboration of the care plan with the oncologists and geriatricians in order to propose the most appropriate treatment for his or her situation.

Keywords: Cancer; Décision thérapeutique; Dépistage; Elderly; Fragilité; Frailty; Personne âgée; Screening; Therapeutic decision.

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Aging
  • Comorbidity
  • Female
  • Geriatric Assessment
  • Geriatricians
  • Humans
  • Male
  • Neoplasms* / complications
  • Neoplasms* / diagnosis
  • Neoplasms* / epidemiology