Anaphylaxis to Stinging Insect Venom

Immunol Allergy Clin North Am. 2022 Feb;42(1):161-173. doi: 10.1016/j.iac.2021.09.003.

Abstract

Hymenoptera stinging insects are common culprits for allergic reactions. Anaphylaxis to insect stings can be life threatening and is associated with a significant risk of recurrence. Insect allergy requires referral to an allergist/immunologist for education and for diagnostic evaluation that will direct further management and treatment. Venom immunotherapy is safe and effective; it prevents sting anaphylaxis in up to 98% of patients. Potential risk factors for side effects during testing and treatment should be assessed for every patient to mitigate risk and to guide treatment recommendations and the duration of immunotherapy.

Keywords: Allergy; Anaphylaxis; Hymenoptera; Immunotherapy; Insect; Stinging; Venom.

Publication types

  • Review

MeSH terms

  • Anaphylaxis* / diagnosis
  • Anaphylaxis* / etiology
  • Anaphylaxis* / therapy
  • Animals
  • Arthropod Venoms*
  • Desensitization, Immunologic
  • Humans
  • Hymenoptera*
  • Insect Bites and Stings*

Substances

  • Arthropod Venoms