Photodynamic therapy in the treatment of perianal condyloma acuminatum with hemorrhoids: A report of two cases

Photodiagnosis Photodyn Ther. 2022 Mar:37:102644. doi: 10.1016/j.pdpdt.2021.102644. Epub 2021 Nov 22.

Abstract

In this work, we used photodynamic therapy(ALA-PDT) to treat 2 patients with perianal hemorrhoids combined with condyloma acuminatum. After 4 photodynamic treatments, the condyloma acuminata skin lesions completely disappeared. At the same time, we unexpectedly found that the patient's hemorrhoids skin lesions had mostly faded, and did not reappear during the half-year follow-up. Photodynamic therapy is satisfactory in the treatment of hemorrhoids combined with condyloma acuminatum, and the recurrence rate is low. We also have found that photodynamic therapy is equally effective on hemorrhoid skin lesions. PDT may be adopted as a new strategy in the study and treatment of hemorrhoids. To the best of our knowledge, no such cases have been reported.

Keywords: Condyloma; Hemmorrhoids; PDT.

Publication types

  • Case Reports

MeSH terms

  • Condylomata Acuminata* / drug therapy
  • Hemorrhoids* / complications
  • Hemorrhoids* / drug therapy
  • Humans
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use

Substances

  • Photosensitizing Agents