Automatic PI-RADS assignment by means of formal methods

Radiol Med. 2022 Jan;127(1):83-89. doi: 10.1007/s11547-021-01431-y. Epub 2021 Nov 25.

Abstract

Introduction and objectives: The Prostate Imaging Reporting and Data System (PI-RADS) version 2 emerged as standard in prostate magnetic resonance imaging examination. The Pi-RADS scores are assigned by radiologists and indicate the likelihood of a clinically significant cancer. The aim of this paper is to propose a methodology to automatically mark a magnetic resonance imaging with its related PI-RADS.

Materials and methods: We collected a dataset from two different institutions composed by DWI ADC MRI for 91 patients marked by expert radiologists with different PI-RADS score. A formal model is generated starting from a prostate magnetic resonance imaging, and a set of properties related to the different PI-RADS scores are formulated with the help of expert radiologists and pathologists.

Results: Our methodology relies on the adoption of formal methods and radiomic features, and in the experimental analysis, we obtain a specificity and sensitivity equal to 1.

Q conclusions: The proposed methodology is able to assign the PI-RADS score by analyzing prostate magnetic resonance imaging with a very high accuracy.

Keywords: Cancer; Classification; Formal methods; Model checking; Prostate; Radiomics.

MeSH terms

  • Diffusion Magnetic Resonance Imaging / methods*
  • Humans
  • Male
  • Patient Acuity
  • Prostate / diagnostic imaging
  • Prostatic Neoplasms / diagnostic imaging*
  • Radiology Information Systems / statistics & numerical data*
  • Reproducibility of Results