Peribiliary Intravascular Fibrin Occlusions and Bile Duct Necrosis in DCD Livers During Ex Situ Perfusion: Prevention With Tissue Plasminogen Activator and Fresh Frozen Plasma

Christopher J E Watson; Rebecca Brais; Rohit Gaurav; Lisa Swift; Corrina Fear; Theodora Foukaneli; Andrew J Butler

doi:10.1097/TP.0000000000003864

Peribiliary Intravascular Fibrin Occlusions and Bile Duct Necrosis in DCD Livers During Ex Situ Perfusion: Prevention With Tissue Plasminogen Activator and Fresh Frozen Plasma

Transplantation. 2021 Dec 1;105(12):e401-e402. doi: 10.1097/TP.0000000000003864.

Authors

Christopher J E Watson^{1

2

3

4}, Rebecca Brais^{1

5}, Rohit Gaurav⁴, Lisa Swift⁴, Corrina Fear⁴, Theodora Foukaneli^{1

6}, Andrew J Butler^{1

2

3

4}

Affiliations

¹ Cambridge NIHR Biomedical Research Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom.
² NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge Biomedical Campus, Cambridge, United Kingdom.
³ University of Cambridge Department of Surgery, Addenbrooke's Hospital, Cambridge, United Kingdom.
⁴ The Roy Calne Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom.
⁵ Department of Pathology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.
⁶ Department of Haematology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

PMID: 34818309
DOI: 10.1097/TP.0000000000003864

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bile Ducts / surgery
Fibrin*
Humans
Liver
Necrosis
Perfusion
Plasma
Tissue Plasminogen Activator*

Substances

Fibrin
Tissue Plasminogen Activator

Grants and funding

DH_/Department of Health/United Kingdom