Caries intensity and Streptococcus mutans in the saliva of patients with Turner syndrome

Aida Kusiak; Barbara Kochańska; Dariusz Świetlik; Aleksandra Cydejko; Adrian Maj

doi:10.1016/j.sdentj.2020.12.003

Caries intensity and Streptococcus mutans in the saliva of patients with Turner syndrome

Saudi Dent J. 2021 Nov;33(7):448-452. doi: 10.1016/j.sdentj.2020.12.003. Epub 2020 Dec 16.

Authors

Aida Kusiak¹, Barbara Kochańska², Dariusz Świetlik³, Aleksandra Cydejko¹, Adrian Maj¹

Affiliations

¹ Department of Periodontology and Oral Mucosa Diseases, Medical University of Gdańsk, Poland.
² Department of Conservative Dentistry, Medical University of Gdańsk, Poland.
³ Department of Biostatistics and Neural Networks, Medical University of Gdańsk, Poland.

Abstract

Aim: The aim of this study was to evaluate the caries intensity and Streptococcus mutans (SM) counts in patients with Turner syndrome.

Materials and methods: Nineteen patients aged 20-40 years were clinically and cytogenetically diagnosed with Turner syndrome (45, X). The karyotype was determined by chromosome analysis of peripheral blood lymphocytes. The control group comprised 47 healthy women aged 21-40 years. Both groups included non-smokers with no specific diet, such as a vegetarian or vegan diet, who were generally healthy with good oral hygiene and periodontal condition. Patients treated with antibiotics or steroid preparations in the past 6 months or with diseases or conditions that might affect the oral mucosal environment, such as disorders of salivary secretion and diabetes, were excluded from the study. Decayed, missing, and filled teeth (DMFT) scores and SM counts in saliva were determined.

Results: No colony growth of SM was noticed in 53% of patients with Turner syndrome and 4.2% of controls (p < 0.001). Colony counts of SM ≥ 10⁵ in saliva were observed in none of the patients with Turner syndrome but in 66% of controls (p < 0.001). The mean DMFT score was 1.63 ± 2.52 in patients with Turner syndrome and 14.49 ± 6.88 in controls. Statistically significant differences between the two groups were observed (p < 0.05).

Conclusion: Patients with genetic disorders may have different severities of caries and SM counts in saliva compared to those without genetic disorders. Further studies on saliva properties and genes located on the X chromosome could contribute to determining the effect of the X chromosome on the pathological processes in the oral cavity.

Keywords: Caries; Streptococcus Mutans; Turner syndrome.