Epilepsy Syndromes: Current Classifications and Future Directions

Neurosurg Clin N Am. 2022 Jan;33(1):113-134. doi: 10.1016/j.nec.2021.09.009. Epub 2021 Oct 27.

Abstract

This review describes the clinical presentations and treatment options for commonly recognized epilepsy syndromes in the pediatric age group, based on the 2017 International League Against Epilepsy classification. Structural epilepsies that are amenable to surgical intervention are discussed. Lastly, emerging technologies are reviewed that are expanding our knowledge of underlying epilepsy pathologies and will guide future syndromic classification systems including genetic testing and tissue repositories.

Keywords: Epilepsy surgery; Epilepsy syndromes; Precision medicine; Structural epilepsy.

Publication types

  • Review

MeSH terms

  • Child
  • Epilepsy* / diagnosis
  • Epilepsy* / therapy
  • Epileptic Syndromes*
  • Humans