Anesthesia strategy for factor X deficiency coagulopathy: case report

Braz J Anesthesiol. 2022 Nov-Dec;72(6):816-818. doi: 10.1016/j.bjane.2021.08.024. Epub 2021 Nov 17.

Abstract

Factor X deficiency ranks among the rarest coagulopathies and has a variable presentation spectrum. We intend to present a proposal for anesthesia protocol for individuals with the coagulopathy. The excision of an ovarian neoplasm was proposed for a 26-year-old, female, ASA II patient, with congenital Factor X deficiency. Physical examination and lab tests were normal, except for Prothrombin Time (PT) 22.1s (VR: 8-14s), International Normalized Ratio (INR) 1.99 (VR: 0.8-1.2) and Activated Partial Thromboplastin Time (aPTT) 41.4s (VR: 25-37s). We concluded that a history of bleeding should always be investigated, along with a pre-anesthetic coagulation study.

Keywords: Anesthesia; Factor X; Management.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anesthesia* / adverse effects
  • Blood Coagulation Disorders* / diagnosis
  • Blood Coagulation Disorders* / etiology
  • Factor X Deficiency* / complications
  • Female
  • Humans
  • Partial Thromboplastin Time
  • Prothrombin Time