Amyotrophic lateral sclerosis is over-represented in two Huntington's disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion

Acta Neuropathol. 2022 Jan;143(1):105-108. doi: 10.1007/s00401-021-02385-1. Epub 2021 Nov 20.

Richard A Hickman^{1

2}, Ramita Dewan³, Etty Cortes⁴, Bryan J Traynor³, Karen Marder^{5

6}, Jean-Paul Vonsattel^{7

6}

¹ Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. hickmanr@mskcc.org.
² Department of Pathology and Cell Biology, Columbia University Irving Medical Center and New York Presbyterian Hospital, 630 W 168th Street, New York, NY, 10032, USA. hickmanr@mskcc.org.
³ Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, 20892, USA.
⁴ Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
⁵ Department of Neurology and Psychiatry, Columbia University Irving Medical Center, New York, USA.
⁶ Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA.
⁷ Department of Pathology and Cell Biology, Columbia University Irving Medical Center and New York Presbyterian Hospital, 630 W 168th Street, New York, NY, 10032, USA.

No abstract available

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