Prevention of Mother-to-Child Human Immunodeficiency Virus Transmission in Resource-Limited Countries

Pediatr Clin North Am. 2022 Feb;69(1):1-18. doi: 10.1016/j.pcl.2021.08.007.

Abstract

The first pediatric AIDS cases were reported in 1982. A decade later, the World Health Organization estimated there were more than 500,000 pediatric AIDS cases resulting from mother-to-child transmission, 90% of which were in sub-Saharan Africa. Although the rate of new infections globally has been cut in half since the peak of the pandemic, human immunodeficiency virus (HIV) remains a public health threat, and rates of new infections continue to increase in some regions. Mother-to-child transmission of HIV has now been virtually eliminated in many parts of the world but remains an issue in resource-limited countries.

Keywords: Antiretroviral therapy (ART); Guidelines; HIV; Prevention of mother-to-child transmission (PMTCT); Resource-limited.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Africa South of the Sahara
  • Anti-Retroviral Agents / therapeutic use*
  • Breast Feeding
  • Female
  • HIV
  • HIV Infections / prevention & control*
  • HIV Infections / transmission*
  • Health Resources
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Middle Aged
  • Mothers
  • Pregnancy
  • Pregnancy Complications, Infectious / prevention & control*
  • Viral Load
  • World Health Organization
  • Young Adult

Substances

  • Anti-Retroviral Agents