Electrodeposited cobalt hexacyanoferrate electrode as a non-enzymatic glucose sensor under neutral conditions

Abstract

A CoFe Prussian blue analogue (CoFe PB) modified FTO electrode, prepared via a facile electrodeposition method, is investigated as a non-enzymatic glucose sensor under neutral conditions. The electrode exhibits a linear detection of glucose in the 0.1-8.2 mmol/L range with a detection limit of 67 μM, a sensitivity of 18.69 μA/mM.cm², and a fast response time of less than 7 s under neutral conditions. Its stability is confirmed with both electrochemical experiments and characterization studies performed on the pristine and post-mortem electrode. We also conducted a comprehensive electrochemical analysis to elucidate the identity of the active site and the glucose oxidation mechanism on the Prussian blue surface.

Keywords: Amperometric sensing; Cobalt hexacyanoferrate film; Electrodeposition; Glucose sensor; Modified electrode; Non-enzymatic; Prussian blue analogue.