Objective: To investigate the application of traditional Chinese medicine (TCM) syndrome differentiation in identification of body constitution of hypertensive and diabetic patients.
Methods: A total of 110 hypertensive patients with diabetes treated in our hospital were enrolled in this study, and were divided into a study group (SG, n=60) and a control group (CG, n=50) according to different intervention methods. Patients in the CG received conventional western medical intervention for hypertension and diabetes, while patients in the SG received body constitution-identified TCM syndrome differentiation intervention additionally. The changes of blood pressure and plasma glucose during the intervention were compared between the two groups, the clinical effect and quality of life of the two groups were evaluated, and multivariate stepwise Logistic regression analysis on influencing factor of TCM body constitution was conducted.
Results: Compared with that before intervention, the proportion of gentleness constitution in the SG showed a significant increase (P<0.05) after intervention. Dynamic analysis during the intervention showed that patients in the SG had lower systolic blood pressure (SBP), diastolic blood pressure (DBP), lower level of fasting plasma glucose (GLU) and 2-h postprandial plasma glucose (2hPG) than the CG from 1 to 12 months after intervention (P<0.05). Patients in the SG scored higher than the CG on all SF-36 dimensions after intervention (P<0.05). Multivariate stepwise Logistic regression analysis showed that dampness-heat constitution, blood-stasis constitution, Yin-deficiency constitution and phlegm-dampness constitution were the main risk factors for hypertension with diabetes (P<0.05).
Conclusion: Body constitution-identified TCM syndrome differentiation treatment for hypertensive patients with diabetes is effective, which can significantly improve the plasma glucose and blood pressure indices of patients. Dampness-heat constitution, blood-stasis constitution, Yin-deficiency constitution and phlegm-dampness constitution are the risk factors for hypertension with diabetes.
Keywords: Traditional Chinese medicine syndrome differentiation; application; body constitution identification; diabetes; hypertension.
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