Hydroxycinnamic Acids and Their Related Synthetic Analogs: An Update of Pharmacological Activities

Mini Rev Med Chem. 2022;22(11):1516-1544. doi: 10.2174/1389557521666211116122615.

Abstract

The hydroxycinnamic acid scaffold is extremely versatile with various biological activities. This review will highlight the progress of the biological activities of hydroxycinnamic acids and their related synthetic analogs, including recently reported anti-cancer, anti-inflammatory, and antioxidant activities.

Keywords: Hydroxycinnamic acids; anti-cancer; anti-inflammatory; antioxidant; caffeic acid phenethyl ester (CAPE); pharmacological activities.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants / pharmacology
  • Caffeic Acids / pharmacology
  • Coumaric Acids / pharmacology
  • Phenylethyl Alcohol* / pharmacology

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Caffeic Acids
  • Coumaric Acids
  • Phenylethyl Alcohol