Detection, Contamination, Toxicity, and Prevention Methods of Ochratoxins: An Update Review

J Agric Food Chem. 2021 Nov 24;69(46):13974-13989. doi: 10.1021/acs.jafc.1c05994. Epub 2021 Nov 16.

Abstract

Ochratoxins (OTs) with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties are thermostable fungal subordinate metabolites. OTs contamination can occur before or after harvesting, during the processing, packing, distribution, and storage of food. Mold development and mycotoxin contamination can occur in any crop or cereal that has not been stored properly for long periods of time and is subjected to high levels of humidity and temperature. Ochratoxin A (OTA) presents a significant health threat to creatures and individuals. There is also a concern of how human interaction with OTA will also express the remains of OTA from feedstuffs into animal-derived items. Numerous approaches have been studied for the reduction of the OTA content in agronomic products. These methods can be classified into two major classes: inhibition of OTA adulteration and decontamination or detoxification of food. A description of the various mycotoxins, the organism responsible for the development of mycotoxins, and their adverse effects are given. In the current paper, the incidence of OTA in various fodder and food materials is discussed, which is accompanied by a brief overview of the OTA mode of synthesis, physicochemical properties, toxic effects of various types of ochratoxins, and OTA decontamination adaptation methods. To our knowledge, we are the first to report on the structure of many naturally accessible OTAs and OTA metabolism. Finally, this paper seeks to be insightful and draw attention to dangerous OTA, which is too frequently neglected and overlooked in farm duplication from the list of discrepancy studies.

Keywords: Ssensors; adsorption; detoxification; ochratoxin; spoilage.

Publication types

  • Review

MeSH terms

  • Animal Feed / analysis
  • Animals
  • Edible Grain / chemistry
  • Food Contamination / analysis
  • Humans
  • Mycotoxins* / toxicity
  • Ochratoxins* / analysis

Substances

  • Mycotoxins
  • Ochratoxins