Rheological investigation of a versatile salecan/curdlan gel matrix

Int J Biol Macromol. 2021 Dec 15;193(Pt B):2202-2209. doi: 10.1016/j.ijbiomac.2021.11.051. Epub 2021 Nov 13.

Abstract

Hydrogel, as a three-dimensional material with high water content, has unique physicochemical and variable mechanical properties. Natural polysaccharide-based composite hydrogels are very popular within medical industry as these viscoelastic materials are non-toxic, biodegradable, bioabsorbable, and biocompatible. This research investigates the engineering of novel composite hydrogels from natural polysaccharides salecan and curdlan without any structural modification and chemical crosslinking. The scanning electron microscopy, Fourier transform infrared spectroscopy and various rheological methods were employed to investigate the morphology, molecular interaction, and flow behavior of the samples respectively. The key rheological parameters were compared using the Power Law, Herschel-Bulkley and Arrhenius models. This is the first study reporting a novel composite hydrogel made from Salecan and Curdlan with ideal elasticity, enhanced thermostability, good injectability, self-recovery and other rheological properties that will pave the way for application in different fields.

Keywords: Composites; Curdlan; Hydrogel; Rheology; Salecan.

MeSH terms

  • Biocompatible Materials / chemistry
  • Elasticity
  • Hydrogels / chemistry*
  • Hydrogen-Ion Concentration
  • Microscopy, Electron, Scanning / methods
  • Rheology / methods
  • Spectroscopy, Fourier Transform Infrared / methods
  • Water / chemistry
  • beta-Glucans / chemistry*

Substances

  • Biocompatible Materials
  • Hydrogels
  • beta-Glucans
  • salecan
  • Water
  • curdlan