Imaging in experimental models of diabetes

Acta Diabetol. 2022 Feb;59(2):147-161. doi: 10.1007/s00592-021-01826-3. Epub 2021 Nov 15.

Abstract

Translational medicine, experimental medicine and experimental animal models, in particular mice and rats, represent a multidisciplinary field that has made it possible to achieve, in the last decades, important scientific progress. In this review, we have summarized the most frequently used imaging animal models, such as ultrasound (US), micro-CT, MRI and the optical imaging methods, and their main implications in diagnostic and therapeutic fields, with a particular focus on diabetes mellitus, a multifactorial disease extremely widespread among the general population.

Keywords: Diabetes; Experimental imaging; Experimental medicine; Experimental models; Murine models.

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus*
  • Disease Models, Animal
  • Humans
  • Magnetic Resonance Imaging
  • Mice
  • Rats
  • Ultrasonography