Magnetic covalent-organic frameworks for the simultaneous extraction of eleven emerging aromatic disinfection byproducts in water samples coupled with UHPLC-MS/MS determination

Shuang Li; Jiping Ma; Gege Wu; Jinhua Li; Xiaoyan Wang; Lingxin Chen

doi:10.1016/j.jhazmat.2021.127687

Magnetic covalent-organic frameworks for the simultaneous extraction of eleven emerging aromatic disinfection byproducts in water samples coupled with UHPLC-MS/MS determination

J Hazard Mater. 2022 Feb 15;424(Pt D):127687. doi: 10.1016/j.jhazmat.2021.127687. Epub 2021 Nov 4.

Authors

Shuang Li¹, Jiping Ma², Gege Wu¹, Jinhua Li³, Xiaoyan Wang⁴, Lingxin Chen⁵

Affiliations

¹ School of Environmental & Municipal Engineering, State-Local Joint Engineering Research Center of Urban Sewage Treatment and Resource Recovery, Qingdao University of Technology, Qingdao 266033, China.
² School of Environmental & Municipal Engineering, State-Local Joint Engineering Research Center of Urban Sewage Treatment and Resource Recovery, Qingdao University of Technology, Qingdao 266033, China. Electronic address: majiping2012@163.com.
³ Research Centre for Coastal Environmental Engineering and Technology, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
⁴ School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
⁵ Research Centre for Coastal Environmental Engineering and Technology, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China. Electronic address: lxchen@yic.ac.cn.

PMID: 34776299
DOI: 10.1016/j.jhazmat.2021.127687

Abstract

A simple method based on magnetic solid-phase extraction (MSPE) was developed for the simultaneous extraction of eleven emerging aromatic disinfection byproducts (DBPs) in water samples coupled with ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) determination. A magnetic covalent-organic framework (COF) material, namely, Fe₃O₄ @TpBD, was facilely synthesized and fully characterized, followed by an MSPE process. Several important MSPE parameters, such as the magnetic ratio, Fe₃O₄ @TpBD amount and sample pH, were systematically investigated. Under optimal conditions, the limits of detection and quantification of this COF-MSPE-UHPLC-MS/MS method were as low as 0.07-1.81 ng/L and 0.24-5.99 ng/L, respectively. Good precision was obtained with relative standard deviations (RSDs) of 1.3-10.9% (intraday) and 4.3-15.9% (interday). Furthermore, the validated method was proven applicable to real water samples; for example, the recoveries were 86.8-115.1% for the secondary effluent, and several DBPs in swimming pool water were detected. Notably, the MSPE process required only 7 min, ensuring that the DBPs were relatively stable during the whole analysis process and that Fe₃O₄ @TpBD demonstrated excellent reusability. The COF-based MSPE method with simplicity, rapidity and efficiency provided an ideal sample pretreatment alternative to determine trace DBPs in complex matrices.

Keywords: Covalent-organic frameworks (COFs); Disinfection byproducts (DBPs); Magnetic SPE; UHPLC–MS/MS; Water samples.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, High Pressure Liquid
Disinfection
Limit of Detection
Magnetic Phenomena
Metal-Organic Frameworks*
Solid Phase Extraction
Tandem Mass Spectrometry*
Water

Substances

Metal-Organic Frameworks
Water