Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Ital J Pediatr. 2021 Nov 14;47(1):226. doi: 10.1186/s13052-021-01180-8.

Abstract

Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.

Keywords: Enteral formulas; NEC; Necrotizing enterocolitis; Neonatology; Pediatric gastroenterology; Pediatric nutrition; Pediatric surgery; Preterm newborns; Very low birth weight infants.

Publication types

  • Observational Study

MeSH terms

  • Enteral Nutrition
  • Enterocolitis, Necrotizing / therapy*
  • Female
  • Gestational Age
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / therapy
  • Infant, Very Low Birth Weight
  • Male
  • Parenteral Nutrition
  • Prospective Studies
  • Vitamins / administration & dosage

Substances

  • Vitamins