Nasal High-Frequency Ventilation

Daniele De Luca; Roberta Centorrino

doi:10.1016/j.clp.2021.07.006

Nasal High-Frequency Ventilation

Clin Perinatol. 2021 Dec;48(4):761-782. doi: 10.1016/j.clp.2021.07.006. Epub 2021 Oct 2.

Authors

Daniele De Luca¹, Roberta Centorrino²

Affiliations

¹ Division of Pediatrics and Neonatal Critical Care, "A.Beclere" Medical Center, Paris Saclay University Hospitals, APHP, Paris - France; Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris - France. Electronic address: dm.deluca@icloud.com.
² Division of Pediatrics and Neonatal Critical Care, "A.Beclere" Medical Center, Paris Saclay University Hospitals, APHP, Paris - France; Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris - France.

PMID: 34774208
DOI: 10.1016/j.clp.2021.07.006

Abstract

Noninvasive high-frequency oscillatory (NHFOV) and percussive (NHFPV) ventilation represent 2 nonconventional techniques that may be useful in selected neonatal patients. We offer here a comprehensive review of physiology, mechanics, and biology for both techniques. As NHFOV is the technique with the wider experience, we also provided a meta-analysis of available clinical trials, suggested ventilatory parameters boundaries, and proposed a physiology-based clinical protocol to use NHFOV.

Keywords: Interface; Neonate; Newborn infant; Noninvasive; Oscillation; Percussive; Rescue; Respiratory support.

Publication types

Meta-Analysis
Review

MeSH terms

High-Frequency Ventilation*
Humans
Infant, Newborn
Infant, Premature
Lung
Noninvasive Ventilation*
Nose