Surface Effect of Nano-Roughened Yttria-Doped Zirconia on Salivary Protein Adhesion

Muhammad Naeem Iqbal; Zhijian James Shen; Tore Bengtsson; Mirva Eriksson

doi:10.3390/ma14216412

Surface Effect of Nano-Roughened Yttria-Doped Zirconia on Salivary Protein Adhesion

Materials (Basel). 2021 Oct 26;14(21):6412. doi: 10.3390/ma14216412.

Authors

Muhammad Naeem Iqbal¹, Zhijian James Shen¹, Tore Bengtsson², Mirva Eriksson¹

Affiliations

¹ Department of Materials and Environmental Chemistry, Stockholm University, 10691 Stockholm, Sweden.
² Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 10691 Stockholm, Sweden.

Abstract

Biocompatibility of yttria (3 mol%) stabilized zirconia ceramics, 3Y-TZP, was affected to a large degree as a result of protein adsorption from human saliva that in turn depends on materials surface properties. Variable nano-roughness levels in 3Y-TZP discs were characterized and tested for specificity and selectivity with respect to size and uptake for human salivary protein.

Keywords: 3 mol% yttria partially stabilized zirconia ceramics (3Y-TZP); alpha-amylase adsorption; nano-surface roughness; protein adsorption; saliva.