We propose a unified description of intersubband absorption saturation for quantum wells inserted in a resonator, both in the weak and strong light-matter coupling regimes. We demonstrate how absorption saturation can be engineered. In particular, we show that the saturation intensity increases linearly with the doping in the strong coupling regime, while it remains doping independent in weak coupling. Hence, countering intuition, the most suitable region to exploit low saturation intensities is not the ultrastrong coupling regime, but is instead at the onset of the strong light-matter coupling. We further derive explicit conditions for the emergence of bistability. This Letter sets the path toward, as yet, nonexistent ultrafast midinfrared semiconductor saturable absorption mirrors (SESAMs) and bistable systems. As an example, we show how to design a midinfrared SESAM with a 3 orders of magnitude reduction in saturation intensity, down to ≈5 kW cm^{-2}.