Use of Buspirone in the Treatment of Nonpharmacological Bruxism: About 4 Cases

Clin Neuropharmacol. 2021 Nov-Dec;44(6):247-249. doi: 10.1097/WNF.0000000000000486.

Abstract

Objective: The aim of the study was to describe the efficacy of buspirone in controlling nonpharmacological awake and sleep bruxism.

Methods: Four cases of nonpharmacological awake and sleep bruxism, one of them with a 20-year-long history, in which buspirone succeeded to control bruxism, are described and discussed.

Results: Two of the 4 cases had sleep bruxism, and the other 2 cases had sleep and awake bruxism. Besides anxiety, no other predisposing condition was identified. Buspirone was effective in reducing bruxism symptoms in the 4 cases. Mean percentage of bruxism reduction after buspirone was ranked as 65% by subjects.

Conclusions: In this small series of cases, buspirone proved effective in the control of nonpharmacological awake and sleep bruxism.

MeSH terms

  • Anxiety
  • Bruxism*
  • Buspirone / therapeutic use
  • Humans
  • Sleep
  • Sleep Bruxism* / drug therapy
  • Wakefulness

Substances

  • Buspirone