Ultrastructural changes in the underactive bladder

Han-Chen Ho; Yung-Hsiang Hsu; Jia-Fong Jhang; Yuan-Hong Jiang; Hann-Chorng Kuo

doi:10.4103/tcmj.tcmj_153_20

Ultrastructural changes in the underactive bladder

Tzu Chi Med J. 2020 Sep 16;33(4):345-349. doi: 10.4103/tcmj.tcmj_153_20. eCollection 2021 Oct-Dec.

Authors

Han-Chen Ho¹, Yung-Hsiang Hsu², Jia-Fong Jhang³, Yuan-Hong Jiang³, Hann-Chorng Kuo³

Affiliations

¹ Department of Anatomy, Tzu Chi University, Hualien, Taiwan.
² Department of Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, and Tzu Chi University, Hualien, Taiwan.
³ Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, and Tzu Chi University, Hualien, Taiwan.

Abstract

Underactive bladder (UAB) is a symptom complex suggestive of detrusor underactivity (DU). Although it implies a primary dysfunction of the detrusor muscle, many other conditions such as advanced age, neurogenic factors, and bladder outlet obstruction also lead to UAB. The current understanding of the pathophysiology directly leading to UAB is limited. We believe that by identifying the morphological changes associated with UAB might shed light on this. Therefore, we searched literature with keywords of electron microscopy, ultrastructure, UAB, and DU to review current ultrastructural evidence concerning UAB.

Keywords: Detrusor underactivity; Electron microscopy; Ultrastructure; Underactive bladder.

Publication types

Review