Single center 5-years' experience of Ozaki procedure: mid-term follow-up

Ann Thorac Surg. 2020 Oct 22:S0003-4975(20)31730-6. doi: 10.1016/j.athoracsur.2020.08.039. Online ahead of print.

Abstract

Background: The Ozaki procedure is an innovative surgical technique aiming at the reconstruction of the aortic valve with autologous pericardium to overcome the limitations of commercially available prostheses.

Methods: We retrospectively analysed 71 patients who underwent Ozaki operation at our centre between October 2014 and February 2020.

Results: No in-hospital death occurred. Freedom from major adverse valve-related events (MAVRE) was 97%. The aortic gradients and transvalvular velocity are significantly lower at the 3-months echocardiographic control than at the pre-discharged echocardiography (10.93 ± 5.38, p= 0,0003 vs 16.24 ± 7.67 p= 0,0004 respectively). The median follow-up period was 20.7 months (range 2 to 47 months). Four patients showed mild/moderate aortic insufficiency (5.6%) and none showed severe aortic valve insufficiency. No patients underwent reoperation.

Conclusions: Mid-term outcome follow-up of Ozaki procedure showed optimal results in term of mortality, transaortic valve gradients, freedom from MAVRE and recurrence of aortic valve insufficiency.