A novel fluorescent probe with aggregation induced emission (AIE) effect based on 1,4-dihydropyridine and its applications

Luminescence. 2022 Jan;37(1):177-185. doi: 10.1002/bio.4159. Epub 2021 Nov 24.

Abstract

A fluorescent hydrazine hydrate probe (DMA) based on 1,4-dihydropyridine derivatives was designed and synthesized. The fluorescence emission peak of this probe is in the near-infrared region (667 nm), which has good selectivity to hydrazine hydrate and low detection limit (11 nM). Importantly, the probe exhibits aggregation-induced emission (AIE) characteristics. In addition, the probe is prepared with a portable test paper to realize the identification of hydrazine hydrate in the solution and the quantitative detection of hydrazine hydrate gas.

Keywords: 1,4-dihydropyridines; aggregation-induced emission (AIE); fluorescent probe; hydrazine hydrate; near-infrared.

MeSH terms

  • Dihydropyridines*
  • Fluorescent Dyes*
  • HeLa Cells
  • Humans
  • Spectrometry, Fluorescence

Substances

  • Dihydropyridines
  • Fluorescent Dyes
  • 1,4-dihydropyridine