Spatiotemporal prediction of COVID-19 cases using inter- and intra-county proxies of human interactions

Nat Commun. 2021 Nov 8;12(1):6440. doi: 10.1038/s41467-021-26742-6.

Abstract

Measurements of human interaction through proxies such as social connectedness or movement patterns have proved useful for predictive modeling of COVID-19, which is a challenging task, especially at high spatial resolutions. In this study, we develop a Spatiotemporal autoregressive model to predict county-level new cases of COVID-19 in the coterminous US using spatiotemporal lags of infection rates, human interactions, human mobility, and socioeconomic composition of counties as predictive features. We capture human interactions through 1) Facebook- and 2) cell phone-derived measures of connectivity and human mobility, and use them in two separate models for predicting county-level new cases of COVID-19. We evaluate the model on 14 forecast dates between 2020/10/25 and 2021/01/24 over one- to four-week prediction horizons. Comparing our predictions with a Baseline model developed by the COVID-19 Forecast Hub indicates an average 6.46% improvement in prediction Mean Absolute Errors (MAE) over the two-week prediction horizon up to 20.22% improvement in the four-week prediction horizon, pointing to the strong predictive power of our model in the longer prediction horizons.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / transmission
  • COVID-19 / virology
  • Cell Phone Use / statistics & numerical data*
  • Forecasting
  • Humans
  • Machine Learning
  • Models, Statistical
  • Population Dynamics
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / isolation & purification
  • Spatio-Temporal Analysis