Importance and results of sterility testing of various products in a microbiology laboratory of eastern India

Indian J Med Microbiol. 2022 Jan-Mar;40(1):138-140. doi: 10.1016/j.ijmmb.2021.10.008. Epub 2021 Nov 3.

Abstract

Components of blood products from Blood bank, stem cells products from Haemotapoietic Stem Cell Transplant unit, CSSD (Central Sterile Supply Department) items, and pharrrmaceutical products, were sterility tested by liquid culture. 2.91% of the total 3122 samples sent for sterility testing from various departments were positive (i.e. showing contamination). CSSD products showed no contamination (0/37); products from blood bank and bone marrow transplant unit showed a contamination rate of 2.03% (47/2307) and 4.64% (31/667) respectively. The average cost of sterility test was Rs. 302 (INR). Sterility test requires stringent aseptic precautions which is resource intensive.

Keywords: Blood products; CSSD; Hematopoietic stem cell products; Microbiology; Sterility testing.

MeSH terms

  • Drug Contamination
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • India
  • Infertility*
  • Sterilization / methods