Thymoma-associated multiorgan autoimmunity with cutaneous only presentation: A case report

SAGE Open Med Case Rep. 2021 Oct 28:9:2050313X211055928. doi: 10.1177/2050313X211055928. eCollection 2021.

Abstract

Thymoma-associated multiorgan autoimmunity disease can be seen in patients with thymomas and presents with features of graft versus host disease. Here, we report a case of a 52-year-old woman with a complex medical history including malignant thymoma, myasthenia gravis, Good's syndrome, and T cell large granular lymphocytic leukemia who presented with a diffuse pruritic rash ultimately found to be compatible with a cutaneous presentation of thymoma-associated multiorgan autoimmunity disease. The eruption heralded the recurrence of the malignant thymoma and the rash was ultimately found to be resistant to a multitude of therapies except for oral corticosteroids.

Keywords: Good’s syndrome; Thymoma; lichen planus; morphea; myasthenia gravis; thymoma-associated multiorgan autoimmunity.