Safety and Effectiveness of Areola-sparing Mastectomy for Breast Cancer With Intraductal Lesions

Anticancer Res. 2021 Nov;41(11):5723-5728. doi: 10.21873/anticanres.15388.

Abstract

Background/aim: Areola-sparing mastectomy (ASM), a conservative mastectomy with nipple hollowing, can be applied to intraductal breast cancer with a tumour-nipple-areola complex (NAC) distance of ≤2 cm. Here, we evaluated the safety and effectiveness of ASM.

Patients and methods: We retrospectively reviewed the surgical outcomes of 61 patients (64 breasts) who underwent ASM between 2016 and 2020.

Results: Of the 64 breasts, 33 (51.6%) underwent ASM because the tumour-NAC distance on preoperative magnetic resonance imaging was ≤2 cm. Two patients had positive excisional margins but these were at the posterior areola surface therefore additional resection was possible. Over a median postoperative observation period of 16 months (range=3-52 months), one patient developed chest wall recurrence that was resected and did not recur again.

Conclusion: For breast cancer with an extensive intraductal component, ASM is a good alternative to nipple-sparing mastectomy because it allows safe resection while maintaining aesthetics.

Keywords: Breast cancer; areola-sparing mastectomy; reconstruction.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Carcinoma, Ductal, Breast / diagnostic imaging
  • Carcinoma, Ductal, Breast / pathology
  • Carcinoma, Ductal, Breast / surgery*
  • Carcinoma, Intraductal, Noninfiltrating / diagnostic imaging
  • Carcinoma, Intraductal, Noninfiltrating / pathology
  • Carcinoma, Intraductal, Noninfiltrating / surgery*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Margins of Excision
  • Mastectomy* / adverse effects
  • Middle Aged
  • Neoplasm, Residual
  • Nipples / surgery*
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome