SARS-CoV-2 infection long time after full vaccination is related to a lack of neutralizing antibodies

Diagn Microbiol Infect Dis. 2022 Jan;102(1):115565. doi: 10.1016/j.diagmicrobio.2021.115565. Epub 2021 Oct 2.

Abstract

SARS-CoV-2 infections after COVID-19 vaccination are not unexpected, but those occurring more than 14 days after second vaccine dose need to be investigated. We describe a well-characterized infection which occurred almost 2 months after full vaccination, and provide the evidence of a link with a lack of anti-SARS-CoV-2 neutralizing antibodies.

Keywords: COVID-19; Infection; Neutralizing antibodies; SARS-CoV-2; Vaccination.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Neutralizing
  • Antibodies, Viral / blood*
  • COVID-19 / prevention & control*
  • COVID-19 / virology*
  • COVID-19 Vaccines / immunology*
  • Humans
  • Immunoglobulin G / blood
  • Male
  • Middle Aged
  • SARS-CoV-2*
  • Vaccination

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral
  • COVID-19 Vaccines
  • Immunoglobulin G