The Relationship Between Alzheimer's Disease and Skin Diseases: A Review

Clin Cosmet Investig Dermatol. 2021 Oct 24:14:1551-1560. doi: 10.2147/CCID.S322530. eCollection 2021.

Abstract

Alzheimer's disease is the most common type of dementia placing a heavy burden on the healthcare system worldwide. Skin diseases are also one of the most common health problems. Several skin diseases are associated with Alzheimer's disease through different mechanisms. This review summarizes the relationship between Alzheimer's disease and several types of skin diseases, including bullous pemphigoid, hidradenitis suppurativa, psoriasis, skin cancer, and cutaneous amyloidosis, and provides suggestions based on these associations. Neurologists, dermatologists, and general practitioners should be aware of the relationship between Alzheimer's disease and skin diseases. Dermatology/neurology consultation or referral is necessary when needed.

Keywords: Alzheimer’s disease; bullous pemphigoid; dementia; hidradenitis suppurativa; psoriasis; skin disease.

Publication types

  • Review