'(m6)A' stands for 'autoimmunity': reading, writing, and erasing RNA modifications during inflammation

Abstract

Covalent RNA modifications that regulate gene expression post transcriptionally, in particular N6-methyladenosine (m⁶A), are emerging as important regulators of autoimmune responses. Here, we highlight new findings describing the functional diversity and specificity of m⁶A modifications and their regulation in the context of autoimmunity.