A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents

Atsushi Nakamura; Tsubasa Yoshimura; Takeshi Ichikawa

doi:10.7759/cureus.19001

A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents

Cureus. 2021 Oct 24;13(10):e19001. doi: 10.7759/cureus.19001. eCollection 2021 Oct.

Authors

Atsushi Nakamura¹, Tsubasa Yoshimura², Takeshi Ichikawa²

Affiliations

¹ Hepatology, Nippon Koukan Hospital, Kawasaki, JPN.
² Gastroenterology, Nippon Koukan Hospital, Kawasaki, JPN.

Abstract

Sofosbuvir/velpatasvir therapy can safely treat hepatitis C virus (HCV)-related decompensated cirrhosis and has been shown to improve liver function at an early stage. However, the pathophysiology of the liver during treatment remains unclear. In this case report, we analyzed hepatic morphology on magnetic resonance imaging during the treatment period and confirmed that liver function and malnutrition were greatly improved with the elimination of HCV, and that rapid hemodynamic changes were occurring in the liver.

Keywords: decompensated cirrhosis; hepatitis c; magnetic resonance elastography; magnetic resonance imaging-proton density fat fraction; protein energy malnutrition (pem).

Publication types

Case Reports