Imaging in Tumor Immunology

Euishin Edmund Kim; Hyewon Youn; Keon Wook Kang

doi:10.1007/s13139-021-00706-6

Imaging in Tumor Immunology

Nucl Med Mol Imaging. 2021 Oct;55(5):225-236. doi: 10.1007/s13139-021-00706-6. Epub 2021 Jul 27.

Authors

Euishin Edmund Kim^{1

2

3}, Hyewon Youn^{2

4}, Keon Wook Kang^{2

4

5}

Affiliations

¹ Department of Radiological Sciences, UCI Medical Center, Orange County, CA USA.
² Department of Nuclear Medicine, Seoul National University Hospital, Seoul, South Korea.
³ Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul, South Korea.
⁴ Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
⁵ Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.

Abstract

Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment. This review summarizes the current tumor immunology and describes new innovative imaging methods with great potential to obtain non-invasive real-time insights into the complex functions of the immune system and into the management of cancer immunotherapy.

Keywords: Cancer immunotherapy; Imaging; Microenvironment; Tumor immunology.

Publication types

Review