High prevalence of obstructive sleep apnea syndrome in Spain's Stroke Belt

J Int Med Res. 2021 Oct;49(10):3000605211053090. doi: 10.1177/03000605211053090.

Abstract

Objective: Spain's so-called Stroke Belt is an area with high prevalence of vascular disease. We aimed to determine the prevalence of undetected obstructive sleep apnea-hypopnea syndrome (OSAHS) among patients with acute ischemic stroke (AIS) in southern Spain.

Methods: We conducted a cross-sectional study at the Virgen Macarena University Hospital Stroke Unit during 2018 to 2019. We included patients <72 hours after AIS with a neuroimaging lesion and performed sleep tests.

Results: Seventy-two patients were included. The median participant age was 72 years. Mean body mass index was 27.07 kg/m2, and 40.28% were daily alcohol drinkers. Hypertension, atrial fibrillation, ischemic cardiomyopathy, and previous stroke were detected in 63.9%, 11.1%, 15.3%, and 17.6% of patients, respectively. Polygraphy was feasible in 91.38% of patients. The prevalence of OSAHS was 84.72% (apnea-hypopnea index ≥5). Patients with moderate and severe OSAHS were more likely to be obese and to have a larger neck circumference and facial palsy. The diagnostic criteria of central sleep apnea syndrome were met in only 1.38% of patients.

Conclusions: The high prevalence of OSAHS found in the Spanish Stroke Belt justifies further investigation and development of a screening program as a strategy to identify patients with undetected OSAHS.

Keywords: Spanish Stroke Belt; ischemic stroke; obstructive sleep apnea–hypopnea syndrome; polygraphy; polysomnography; screening.

MeSH terms

  • Aged
  • Brain Ischemia* / diagnosis
  • Brain Ischemia* / epidemiology
  • Cross-Sectional Studies
  • Humans
  • Prevalence
  • Sleep Apnea, Obstructive* / diagnosis
  • Sleep Apnea, Obstructive* / epidemiology
  • Spain / epidemiology
  • Stroke* / diagnosis
  • Stroke* / epidemiology