A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia

Blood Cancer J. 2021 Oct 30;11(10):175. doi: 10.1038/s41408-021-00568-3.
No abstract available

Publication types

  • Clinical Trial, Phase II
  • Letter
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols*
  • Biomarkers, Tumor / blood*
  • Cytarabine / administration & dosage
  • Female
  • Flavonoids / administration & dosage
  • Humans
  • Leukemia, Myeloid, Acute / blood
  • Leukemia, Myeloid, Acute / drug therapy
  • Male
  • Middle Aged
  • Mitoxantrone / administration & dosage
  • Myeloid Cell Leukemia Sequence 1 Protein*
  • Piperidines / administration & dosage

Substances

  • Biomarkers, Tumor
  • Flavonoids
  • MCL1 protein, human
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Piperidines
  • Cytarabine
  • alvocidib
  • Mitoxantrone