Contrast Pediatric Brain Perfusion: Dynamic Susceptibility Contrast and Dynamic Contrast-Enhanced MR Imaging

Mohannad Ibrahim; Talha Ul Ghazi; Jayapalli Rajiv Bapuraj; Ashok Srinivasan

doi:10.1016/j.mric.2021.06.004

Contrast Pediatric Brain Perfusion: Dynamic Susceptibility Contrast and Dynamic Contrast-Enhanced MR Imaging

Magn Reson Imaging Clin N Am. 2021 Nov;29(4):515-526. doi: 10.1016/j.mric.2021.06.004.

Authors

Mohannad Ibrahim¹, Talha Ul Ghazi², Jayapalli Rajiv Bapuraj¹, Ashok Srinivasan³

Affiliations

¹ Radiology Department, Neuroradiology Division, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
² Michigan State University, College of Human Medicine, 965 Fee Road A110, East Lansing, MI 48824, USA.
³ Radiology Department, Neuroradiology Division, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: ashoks@med.umich.edu.

PMID: 34717842
DOI: 10.1016/j.mric.2021.06.004

Abstract

Magnetic resonance (MR) perfusion is a robust imaging technique that assesses the passage of blood through the cerebral vascular network using a variety of techniques. The applications of MR perfusion have been expanded and is well suited to investigate cerebrovascular diseases and cerebral neoplastic processes in pediatric patients. Assessment of brain perfusion can augment the information obtained on conventional MR imaging and provides additional information on the biological and physiologic features of pediatric brain tumors. Similarly, MR perfusion can help guide the management of a variety of pediatric cerebrovascular diseases, including acute ischemic stroke and Moyamoya syndrome.

Keywords: DCE; DSC; Ischemia; MR perfusion; Pediatric; Tumors.

Publication types

Review

MeSH terms

Brain / diagnostic imaging
Brain Ischemia*
Brain Neoplasms*
Child
Contrast Media
Humans
Magnetic Resonance Imaging
Perfusion
Stroke* / diagnostic imaging

Substances

Contrast Media