In this paper, we give a detailed description of a novel plasma chamber-the Zyflex chamber-that has been specifically designed for complex/dusty plasma research under reduced gravitational influence as realized during parabolic flight or aboard the International Space Station. The cylindrical, radio-frequency driven discharge device includes a variety of innovations that, for example, allow us to flexibly adjust plasma parameters and its volume via enhanced plasma generation control and a movable, multi-segmented electrode system. The new complex/dusty plasma research tool also supports, due to its overall increased size compared to former space based complex plasma experiments such as PKE-Nefedov or PK-3 Plus, much larger particle systems. Additionally, it can be operated at much lower neutral gas pressures, thus reducing the damping of particle motion considerably. Beyond the technical description and particle-in-cell simulation based characterization of the plasma vessel, we show sample results from experiments performed with this device in the laboratory as well as during parabolic flights, both of which clearly demonstrate the new quality of complex/dusty plasma research that becomes accessible with this new plasma device.