Multiple strategies for the treatment of invasive breast carcinoma: A comprehensive prospective

Abstract

In this review, we emphasize on evolving therapeutic strategies and advances in the treatment of breast cancer (BC). This includes small-molecule inhibitors under preclinical and clinical investigation, phytoconstituents with antiproliferative potential, targeted therapies as antibodies and antibody-drug conjugates (ADCs), vaccines as immunotherapeutic agents and peptides as a novel approach inhibiting the interaction of oncogenic proteins. We provide an update of molecules under different phases of clinical investigation which aid in the identification of loopholes or shortcomings that can be overcomed with future breast cancer research.

Keywords: Antibodies; Antibody drug conjugates; Clinical trial; Peptides; Phytopharmaceuticals; Synthetic derivatives; Vaccines.