A neuropeptide making memories

Anna Schroeder; Johannes J Letzkus

doi:10.1016/j.cell.2021.09.036

A neuropeptide making memories

Cell. 2021 Oct 28;184(22):5501-5503. doi: 10.1016/j.cell.2021.09.036.

Authors

Anna Schroeder¹, Johannes J Letzkus²

Affiliations

¹ Max Planck Institute for Brain Research, 60438 Frankfurt, Germany.
² Institute for Physiology, Faculty of Medicine, University of Freiburg, 79108 Freiburg, Germany; Center for Basics in NeuroModulation (NeuroModul Basics), University of Freiburg, 79106 Freiburg, Germany. Electronic address: johannes.letzkus@physiologie.uni-freiburg.de.

PMID: 34715019
DOI: 10.1016/j.cell.2021.09.036

Abstract

Neuropeptides are the most diverse class of signaling molecules in the brain. Despite evidence for their involvement in several behavioral functions, the precise circuit elements and neuronal computations they control remain elusive. In this issue, Melzer et al. (2021) reveal how the neuropeptide GRP facilitates memory in the neocortex.

Publication types

Comment

MeSH terms

Neocortex* / metabolism
Neurons / metabolism
Neuropeptides* / metabolism

Substances

Neuropeptides