Current review of the management of fistulising perianal Crohn's disease

Samuel O Adegbola; Kapil Sahnan; Charlene Twum-Barima; Nusrat Iqbal; Lillian Reza; Phillip Lung; Janindra Warusavitarne; Phil Tozer; Ailsa Hart

doi:10.1136/flgastro-2020-101489

Current review of the management of fistulising perianal Crohn's disease

Frontline Gastroenterol. 2020 Aug 13;12(6):515-523. doi: 10.1136/flgastro-2020-101489. eCollection 2021.

Authors

Samuel O Adegbola^{1

2}, Kapil Sahnan^{1

2}, Charlene Twum-Barima^{1

2}, Nusrat Iqbal^{1

2}, Lillian Reza^{1

2}, Phillip Lung¹, Janindra Warusavitarne^{1

2}, Phil Tozer^{1

2}, Ailsa Hart^{1

2}

Affiliations

¹ St Mark's Hospital and Academic Institute, Harrow, UK.
² Department of Surgery and Cancer, Imperial College London, London, UK.

Abstract

Perianal manifestations of Crohn's disease constitute a distinct disease phenotype commonly affecting patients and conferring an increased risk of disability and disease burden. Much research has gone into management of fistulising manifestations, with biological therapy changing the landscape of treatment. In this article, we discuss the up-to-date surgical and medical management of perianal fistulas, highlighting current consensus management guidelines and the evidence behind them, as well as future directions in management.

Keywords: crohn's disease; gastrointestinal fistulae.