Gender differences in perceived pain and health-related quality of life in people with chronic non-malignant pain: a cross-sectional study

Contemp Nurse. 2021 Apr-Jun;57(3-4):280-289. doi: 10.1080/10376178.2021.1999836. Epub 2021 Nov 17.

Abstract

Background: Chronic pain has a disproportionate impact on members of vulnerable population groups, and women are at substantially greater risk than men of suffering multiple chronic pain disorders. Moreover, one of the aspects most affected by the presence of chronic pain is that of health-related quality of life (HRQoL), worsening over time, as the disease persists.

Objectives: To describe the profile of patients who suffer non-malignant chronic pain, from a gender perspective, and to identify factors related to their HRQoL and mental health.

Design: A cross-sectional study was carried out in patients with chronic non-cancer pain.

Methods: Sociodemographic variables, pain intensity at rest and in motion, SF-36 health questionnaire, anxiety, and depression were evaluated.

Results: The study population consisted of 531 subjects, of whom 64.2% were women. The mean age was 52.9 (SD: 10.4) years. The pain intensity recorded on the visual analogue scale was 6 (SD: 2.7) at rest and 8 (SD: 2) in motion. Physical component score and mental component score of quality of life were worse in women vs men: 33.73 (6.77) vs 32.33 (6.20), for the physical component; 36.89 (12.77) vs 32.91 (11.51), for mental component. Anxiety, depression and pain intensity, showed poorer results in women.

Conclusion: Gender is a factor that should be considered in assessing and managing chronic pain, due to its influence on the perception of pain, and HRQoL.

Impact statement: Gender is an important modifier of the perception of pain, and HRQoL. To achieve a patient-centred approach, nurses should incorporate gender as a differential factor to adapt and individualize pain management and patient education.

Keywords: Chronic pain; gender; pain management; pain measurement; quality of life.

MeSH terms

  • Analgesics, Opioid
  • Chronic Pain*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pain Perception
  • Quality of Life*
  • Sex Factors
  • Surveys and Questionnaires

Substances

  • Analgesics, Opioid