Angina bullosa hemorrhagica: report of two cases

Quintessence Int. 2022 Jan 7;53(2):180-185. doi: 10.3290/j.qi.b2218695.

Abstract

Angina bullosa hemorrhagica (ABH) is a rare benign condition that affects the oral and oropharyngeal mucosa. It is characterized by a rapid eruption of one or more red or magenta blood-filled bullae, which typically involves the soft palate. ABH is a self-limiting condition that heals spontaneously usually within 2 weeks without scarring. ABH is not related to any dermatologic, hematologic, systemic disorders, or other known causes. The etiopathogeneses of ABH are unknown, though several theories have been proposed. Trauma has been suggested as a potential cause for the development of ABH in susceptible individuals. Two cases are presented of ABH, and the differential diagnoses of oral vesiculobullous conditions is discussed. Cognizance and identification of this benign condition is important to prevent misdiagnosis and eventual unwarranted treatment.

Keywords: angina bullosa hemorrhagica; blood-filled blister; oral cavity disease; thrombocytopenia; vesiculobullous.

Publication types

  • Case Reports

MeSH terms

  • Blister / diagnosis
  • Diagnosis, Differential
  • Humans
  • Mouth Diseases* / diagnosis
  • Oral Hemorrhage* / diagnosis
  • Oral Hemorrhage* / etiology