Prevalence and Associations of Vitreomacular Traction: The Beijing Eye Study

Lei Shao; Chuan Zhang; Li Dong; Wen Da Zhou; Rui Heng Zhang; Wen Bin Wei

doi:10.2147/IJGM.S333010

Prevalence and Associations of Vitreomacular Traction: The Beijing Eye Study

Int J Gen Med. 2021 Oct 21:14:7059-7064. doi: 10.2147/IJGM.S333010. eCollection 2021.

Authors

Lei Shao¹, Chuan Zhang¹, Li Dong¹, Wen Da Zhou¹, Rui Heng Zhang¹, Wen Bin Wei¹

Affiliation

¹ Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.

Abstract

Purpose: To explore the prevalence and associations of vitreous macular traction (VMT) in Chinese population.

Methods: A population-based cross-sectional study with 3468 individuals (mean age of 64.6 ± 9.8 years) based on Beijing Eye Study 2011. Participants underwent detailed ophthalmic examinations, including spectral domain optical coherence tomography (SD-OCT). VMT was defined as abnormal posterior vitreous detachment with anatomical deformation of the fovea, which may include pseudocyst, macular schisis, cystoid macular edema, and subretinal fluid.

Main outcome measure: Prevalence of VMT.

Results: A VMT was detected in 151 (2.3%) eyes (prevalence rate (mean ± SE): 2.3± 0.2%; 95% CI: 1.9%, 2.7%) of 80 (2.4%) subjects (prevalence rate: 2.4± 0.3%; 95% CI: 1.9%, 2.9%). Mean age of all subjects with VMT was 70.1± 8.7 years (median, 70.0 years; range, 50-90 years), mean refractive error was -0.22 ± 2.38D (median, 0.25 D; range, -15.00 to 5.25D). In multivariate analysis, prevalence of VMT was associated with elder age (P=0.001, OR 1.06), female gender (P = 0.036, OR 1.77), subfoveal retinal thickness (P = 0.005, OR 1.01), and subfoveal choroidal thickness (P = 0.026, OR 0.10).

Conclusion: In adult Chinese in Greater Beijing, the prevalence of VMT was 2.3% for eyes or 2.4% for subjects. While it was associated with elder age, female gender, thicker subfoveal retinal thickness and thinner subfoveal choroidal thickness.

Keywords: optical coherence tomography; the Beijing Eye Study; vitreous macular traction.

Grants and funding

This study was supported by National Natural Science Foundation of China (No. 82000916). The priming scientific research foundation for the junior researcher in Beijing Tongren Hospital, Capital Medical University (2016-YJJ-ZLL-009); Beijing Hospitals Authority Youth Programme, code: QML20180204; The priming scientific research foundation for the junior researcher in Beijing Tongren Hospital, Capital Medical University (No.2018-YJJ-ZZL-045). Dongcheng District Outstanding Talent Nurturing Program (2020-dchrcpyzz-42).