Hospital outbreak of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant in partially and fully vaccinated patients and healthcare workers in Toronto, Canada

Erica K Susky; Susy Hota; Irene E Armstrong; Tony Mazzulli; Shaindel Kestenberg; Leanne K Casaubon; John Granton; Carly Rebelo; Erika Bartels; Jeff Wrana; Alon Vaisman

doi:10.1017/ice.2021.471

Hospital outbreak of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant in partially and fully vaccinated patients and healthcare workers in Toronto, Canada

Infect Control Hosp Epidemiol. 2023 Feb;44(2):328-331. doi: 10.1017/ice.2021.471. Epub 2021 Oct 28.

Authors

Erica K Susky¹, Susy Hota^{1

2

3}, Irene E Armstrong⁴, Tony Mazzulli⁵, Shaindel Kestenberg⁶, Leanne K Casaubon^{3

7}, John Granton^{3

6

8}, Carly Rebelo^{1

2}, Erika Bartels⁴, Jeff Wrana⁹, Alon Vaisman^{1

2

3}

Affiliations

¹ Infection Prevention and Control Department, University Health Network, Toronto, Ontario, Canada.
² Division of Infectious Diseases, University Health Network, Toronto, Ontario, Canada.
³ Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
⁴ Toronto Public Heath, Toronto, Ontario, Canada.
⁵ Department of Microbiology, Mount Sinai Health System and University Health Network, Toronto, Ontario, Canada.
⁶ Department of Health Services, University Health Network, Toronto, Ontario, Canada.
⁷ Division of Neurology, University Health Network, Toronto, Ontario, Canada.
⁸ Division of Pulmonary and Critical Care, University Health Network, Toronto, Ontario, Canada.
⁹ Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital, Toronto, Ontario, Canada.

Abstract

The severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant is highly transmissible, and current vaccines may have reduced effectiveness in preventing symptomatic infection. Using epidemiological and genomic analyses, we investigated an outbreak of the variant in an acute-care setting among partially and fully vaccinated individuals. Effective outbreak control was achieved using standard measures.

Keywords: COVID-19; nosocomial transmission; outbreak.

MeSH terms

COVID-19* / epidemiology
COVID-19* / prevention & control
Canada / epidemiology
Disease Outbreaks
Health Personnel
Hospitals
Humans
SARS-CoV-2 / genetics
Virus Diseases*

Supplementary concepts

SARS-CoV-2 variants